Publications and associated numbers were identified in ISI Web of Knowledge using search terms: stem cells[topic] AND Singapore [address]. PubMed links to the listed publication are provided. All publications for 2008 and 2009 are provided and only highly cited publications from 2003-07.

Top 20 cited paper    2009    2008    2007    2006    2005    2004    2003

2008 Publications

The physiology and pathology of the EMT. Meeting on the epithelial-mesenchymal transition.

Acloque H, Thiery JP, Nieto MA.
EMBO Rep. 2008 Apr;9(4):322-6. Epub 2008 Mar 7. No abstract available.

PMID : 18323854 [PubMed - indexed for MEDLINE]

Clinical applications of blood-derived and marrow-derived stem cells for nonmalignant diseases.

Burt RK, Loh Y, Pearce W, Beohar N, Barr WG, Craig R, Wen Y, Rapp JA, Kessler J.
JAMA. 2008 Feb 27;299(8):925-36. Review.

PMID : 18314435 [PubMed - indexed for MEDLINE]

Differentiated fibroblastic progenies of human embryonic stem cells for toxicology screening.

Cao T, Lu K, Fu X, Heng BC.
Cloning Stem Cells. 2008 Mar;10(1):1-10.

PMID : 18241121 [PubMed - indexed for MEDLINE]

A role for TAZ in migration, invasion, and tumorigenesis of breast cancer cells.

Chan SW, Lim CJ, Guo K, Ng CP, Lee I, Hunziker W, Zeng Q, Hong W.
Cancer Res. 2008 Apr 15;68(8):2592-8.

PMID : 18413727 [PubMed - indexed for MEDLINE]

Zebrafish cdx1b regulates expression of downstream factors of Nodal signaling during early endoderm formation.

Cheng PY, Lin CC, Wu CS, Lu YF, Lin CY, Chung CC, Chu CY, Huang CJ, Tsai CY, Korzh S, Wu JL, Hwang SP.
Development. 2008 Mar;135(5):941-52. Epub 2008 Jan 30.

PMID : 18234726 [PubMed - indexed for MEDLINE]

Drosophila neuroblast asymmetric divisions: cell cycle regulators, asymmetric protein localization, and tumorigenesis.

Chia W, Somers WG, Wang H.
J Cell Biol. 2008 Jan 28;180(2):267-72. Epub 2008 Jan 21. Review.

PMID : 18209103 [PubMed - indexed for MEDLINE]

Autogeneic feeders for the culture of undifferentiated human embryonic stem cells in feeder and feeder-free conditions.

Choo A, Ngo AS, Ding V, Oh S, Kiang LS.
Methods Cell Biol. 2008;86:15-28.

PMID : 18442642 [PubMed - indexed for MEDLINE]

In vitro evaluation of fibrin mat and Tegaderm wound dressing for the delivery of keratinocytes--implications of their use to treat burns.

Chua AW, Ma DR, Song IC, Phan TT, Lee ST, Song C.
Burns. 2008 Mar;34(2):175-80. Epub 2007 Oct 29.

PMID : 18029101 [PubMed - indexed for MEDLINE]

Liver stem cells: a scientific and clinical perspective.

Dan YY, Yeoh GC.
J Gastroenterol Hepatol. 2008 May;23(5):687-98. Review.

PMID : 18410603 [PubMed - indexed for MEDLINE]

Do cells let-7 determine stemness?

Dröge P, Davey CA.
Cell Stem Cell. 2008 Jan 10;2(1):8-9.

PMID : 18371414 [PubMed - indexed for MEDLINE]

Enhanced differentiation of mesenchymal stem cells co-cultured with ligament fibroblasts on gelatin/silk fibroin hybrid scaffold.

Fan H, Liu H, Toh SL, Goh JC.
Biomaterials. 2008 Mar;29(8):1017-27. Epub 2007 Nov 26.

PMID : 18023476 [PubMed - indexed for MEDLINE]

Insulin redirects differentiation from cardiogenic mesoderm and endoderm to neuroectoderm in differentiating human embryonic stem cells.

Freund C, Ward-van Oostwaard D, Monshouwer-Kloots J, van den Brink S, van Rooijen M, Xu X, Zweigerdt R, Mummery C, Passier R.
Stem Cells. 2008 Mar;26(3):724-33. Epub 2007 Dec 20.

PMID : 18096723 [PubMed - indexed for MEDLINE]

The use of multiple displacement amplification to amplify complex DNA libraries.

Fullwood MJ, Tan JJ, Ng PW, Chiu KP, Liu J, Wei CL, Ruan Y.
Nucleic Acids Res. 2008 Mar;36(5):e32. Epub 2008 Feb 19.

PMID : 18285362 [PubMed - indexed for MEDLINE]

Enhanced cardiomyogenesis of human embryonic stem cells by a small molecular inhibitor of p38 MAPK.

Graichen R, Xu X, Braam SR, Balakrishnan T, Norfiza S, Sieh S, Soo SY, Tham SC, Mummery C, Colman A, Zweigerdt R, Davidson BP.
Differentiation. 2008 Apr;76(4):357-70. Epub 2007 Nov 15.

PMID : 18021257 [PubMed - indexed for MEDLINE]

An autologous cell lysate extract from human embryonic stem cell (hESC) derived osteoblasts can enhance osteogenesis of hESC.

Heng BC, Toh WS, Pereira BP, Tan BL, Fu X, Liu H, Lu K, Yeo JF, Cao T.
Tissue Cell. 2008 Jun;40(3):219-28. Epub 2008 Feb 1.

PMID : 18242655 [PubMed - indexed for MEDLINE]

RUNX genes in development and cancer: regulation of viral gene expression and the discovery of RUNX family genes.

Ito Y.
Adv Cancer Res. 2008;99:33-76. Review.

PMID : 18037406 [PubMed - indexed for MEDLINE]

Crystal structure and DNA binding of the homeodomain of the stem cell transcription factor Nanog.

Jauch R, Ng CK, Saikatendu KS, Stevens RC, Kolatkar PR.
J Mol Biol. 2008 Feb 22;376(3):758-70. Epub 2007 Dec 4.

PMID : 18177668 [PubMed - indexed for MEDLINE]

A core Klf circuitry regulates self-renewal of embryonic stem cells.

Jiang J, Chan YS, Loh YH, Cai J, Tong GQ, Lim CA, Robson P, Zhong S, Ng HH.
Nat Cell Biol. 2008 Mar;10(3):353-60. Epub 2008 Feb 10.

PMID : 18264089 [PubMed - indexed for MEDLINE]

DNA methyltransferase 3B (DNMT3B) mutations in ICF syndrome lead to altered epigenetic modifications and aberrant expression of genes regulating development, neurogenesis and immune function.

Jin B, Tao Q, Peng J, Soo HM, Wu W, Ying J, Fields CR, Delmas AL, Liu X, Qiu J, Robertson KD.
Hum Mol Genet. 2008 Mar 1;17(5):690-709. Epub 2007 Nov 20.

PMID : 18029387 [PubMed - indexed for MEDLINE]

Nonmyeloablative allogeneic hematopoietic stem cell transplant using mismatched/haploidentical donors: a review.

Koh LP, Chao NJ.
Blood Cells Mol Dis. 2008 Jan-Feb;40(1):20-4. Epub 2007 Sep 19. Review.

PMID : 17884641 [PubMed - indexed for MEDLINE]

Proteome biology of stem cells: a new joint HUPO and ISSCR initiative.

Krijgsveld J, Whetton AD, Lee B, Lemischka I, Oh S, Pera M, Mummery C, Heck AJ.
Mol Cell Proteomics. 2008 Jan;7(1):204-5. No abstract available.

PMID : 18178583 [PubMed - indexed for MEDLINE]

Detailed characterization of the mouse embryonic stem cell transcriptome reveals novel genes and intergenic splicing associated with pluripotency.

Kunarso G, Wong KY, Stanton LW, Lipovich L.
BMC Genomics. 2008 Apr 9;9:155.

PMID : 18400104 [PubMed - indexed for MEDLINE]

The R246S hot-spot p53 mutant exerts dominant-negative effects in embryonic stem cells in vitro and in vivo.

Lee MK, Sabapathy K.
J Cell Sci. 2008 Jun 1;121(Pt 11):1899-906. Epub 2008 May 13.

PMID : 18477611 [PubMed - indexed for MEDLINE]

A comparison of rabbit mesenchymal stem cells and anterior cruciate ligament fibroblasts responses on combined silk scaffolds.

Liu H, Fan H, Toh SL, Goh JC.
Biomaterials. 2008 Apr;29(10):1443-53. Epub 2007 Dec 21.

PMID : 18155134 [PubMed - indexed for MEDLINE]

The interaction between a combined knitted silk scaffold and microporous silk sponge with human mesenchymal stem cells for ligament tissue engineering.

Liu H, Fan H, Wang Y, Toh SL, Goh JC.
Biomaterials. 2008 Feb;29(6):662-74. Epub 2007 Nov 13.

PMID : 17997479 [PubMed - indexed for MEDLINE]

Tendon tissue engineering using scaffold enhancing strategies.

Liu Y, Ramanath HS, Wang DA.
Trends Biotechnol. 2008 Apr;26(4):201-9. Epub 2008 Mar 4. Review.

PMID : 18295915 [PubMed - indexed for MEDLINE]

Molecular framework underlying pluripotency.

Loh YH, Ng JH, Ng HH.
Cell Cycle. 2008 Apr 1;7(7):885-91. Epub 2008 Jan 22. Review.

PMID : 18414030 [PubMed - indexed for MEDLINE]

Neural differentiation and potential use of stem cells from the human umbilical cord for central nervous system transplantation therapy.

Low CB, Liou YC, Tang BL.
J Neurosci Res. 2008 Jun;86(8):1670-9. Review.

PMID : 18241062 [PubMed - indexed for MEDLINE]

Morphological and functional characterization of predifferentiation of myelinating glia-like cells from human bone marrow stromal cells through activation of F3/Notch signaling in mouse retina.

Lu L, Chen X, Zhang CW, Yang WL, Wu YJ, Sun L, Bai LM, Gu XS, Ahmed S, Dawe GS, Xiao ZC.
Stem Cells. 2008 Feb;26(2):580-90. Epub 2007 Nov 1.

PMID : 17975227 [PubMed - indexed for MEDLINE]

Electrospun nanofiber scaffolds for rapid and rich capture of bone marrow-derived hematopoietic stem cells.

Ma K, Chan CK, Liao S, Hwang WY, Feng Q, Ramakrishna S.
Biomaterials. 2008 May;29(13):2096-103.

PMID : 18289666 [PubMed - indexed for MEDLINE]

MyoCell, a cell-based, autologous skeletal myoblast therapy for the treatment of cardiovascular diseases.

Haider HKh, Lei Y, Ashraf M.
Curr Opin Mol Ther. 2008 Dec;10(6):611-21.

PMID : 19051139 [PubMed - indexed for MEDLINE]

Human stem cells for modeling neurological disorders: accelerating the drug discovery pipeline.

Crook JM, Kobayashi NR.
J Cell Biochem. 2008 Dec 15;105(6):1361-6. Review.

PMID : 18980214 [PubMed - indexed for MEDLINE]

Taking stem cells to the clinic: Major challenges.

Bongso A, Fong CY, Gauthaman K.
J Cell Biochem. 2008 Dec 15;105(6):1352-60. Review.

PMID : 18980213 [PubMed - indexed for MEDLINE]

Characterization of a side population of astrocytoma cells in response to temozolomide.

Chua C, Zaiden N, Chong KH, See SJ, Wong MC, Ang BT, Tang C.
J Neurosurg. 2008 Nov;109(5):856-66.

PMID : 18976075 [PubMed - indexed for MEDLINE]

Chromatin and the cell cycle meet in Madrid.

Dominguez M, Berger F.
Development. 2008 Nov;135(21):3475-80.

PMID : 18849527 [PubMed - indexed for MEDLINE]

Induced Pluripotent Stem Cells (iPSC)--can direct delivery of transcription factors into the cytosol overcome the perils of permanent genetic modification?

Heng BC, Richards M.
Minim Invasive Ther Allied Technol. 2008;17(5):326-7; author reply 328. No abstract available.

PMID : 18846464 [PubMed - indexed for MEDLINE]

Numb mediates the interaction between Wnt and Notch to modulate primitive erythropoietic specification from the hemangioblast.

Cheng X, Huber TL, Chen VC, Gadue P, Keller GM.
Development. 2008 Oct;135(20):3447-58. Epub 2008 Sep 17.

PMID : 18799543 [PubMed - indexed for MEDLINE]

Generation of high-level stable transgene expressing human embryonic stem cell lines using Chinese hamster elongation factor-1 alpha promoter system.

Chan KK, Wu SM, Nissom PM, Oh SK, Choo AB.
Stem Cells Dev. 2008 Aug;17(4):825-36.

PMID : 18788934 [PubMed - indexed for MEDLINE]

Induced pluripotent stem cells and human disease.

Colman A.
Cell Stem Cell. 2008 Sep 11;3(3):236-7. No abstract available.

PMID : 18786410 [PubMed - indexed for MEDLINE]

TGF-beta3: A promising growth factor in engineered organogenesis.

Hao J, Varshney RR, Wang DA.
Expert Opin Biol Ther. 2008 Oct;8(10):1485-93. Review.

PMID : 18774917 [PubMed - indexed for MEDLINE]

Gene Transfer and Living Release of Transforming Growth Factor-beta3 for Cartilage Tissue Engineering Applications.

Hao J, Yao Y, Varshney RR, Wang L, Prakash C, Li H, Wang DA.
Tissue Eng Part C Methods. 2008 Dec;14(4):273-280.

PMID : 18771416 [PubMed - as supplied by publisher]

Electrospun poly(epsilon-caprolactone)/gelatin nanofibrous scaffolds for nerve tissue engineering.

Ghasemi-Mobarakeh L, Prabhakaran MP, Morshed M, Nasr-Esfahani MH, Ramakrishna S.
Biomaterials. 2008 Dec;29(34):4532-9. Epub 2008 Aug 30.

PMID : 18757094 [PubMed - indexed for MEDLINE]

A simple and reliable electroporation method for human bone marrow mesenchymal stem cells.

Helledie T, Nurcombe V, Cool SM.
Stem Cells Dev. 2008 Aug;17(4):837-48.

PMID : 18752428 [PubMed - indexed for MEDLINE]

Nonhuman primate allogeneic hematopoietic stem cell transplantation by intraosseus vs intravenous injection: Engraftment, donor cell distribution, and mechanistic basis.

Feng Q, Chow PK, Frassoni F, Phua CM, Tan PK, Prasath A, Khee Hwang WY.
Exp Hematol. 2008 Nov;36(11):1556-66. Epub 2008 Aug 22.

PMID : 18722042 [PubMed - indexed for MEDLINE]

Zfp143 regulates Nanog through modulation of Oct4 binding.

Chen X, Fang F, Liou YC, Ng HH.
Stem Cells. 2008 Nov;26(11):2759-67. Epub 2008 Aug 7.

PMID : 18687992 [PubMed - in process]

First trimester embryo-fetoscopic and ultrasound-guided fetal blood sampling for ex vivo viral transduction of cultured human fetal mesenchymal stem cells.

Chan J, Kumar S, Fisk NM.
Hum Reprod. 2008 Nov;23(11):2427-37. Epub 2008 Aug 6.

PMID : 18687673 [PubMed - in process]

Evolution of the mammalian transcription factor binding repertoire via transposable elements.

Bourque G, Leong B, Vega VB, Chen X, Lee YL, Srinivasan KG, Chew JL, Ruan Y, Wei CL, Ng HH, Liu ET.
Genome Res. 2008 Nov;18(11):1752-62. Epub 2008 Aug 5.

PMID : 18682548 [PubMed - indexed for MEDLINE]

Self-renewal made simple.

Dunn NR.
Cell Stem Cell. 2008 Jul 3;3(1):7-8.

PMID : 18593552 [PubMed - indexed for MEDLINE]

Integration of external signaling pathways with the core transcriptional network in embryonic stem cells.

Chen X, Xu H, Yuan P, Fang F, Huss M, Vega VB, Wong E, Orlov YL, Zhang W, Jiang J, Loh YH, Yeo HC, Yeo ZX, Narang V, Govindarajan KR, Leong B, Shahab A, Ruan Y, Bourque G, Sung WK, Clarke ND, Wei CL, Ng HH.
Cell. 2008 Jun 13;133(6):1106-17.

PMID : 18555785 [PubMed - indexed for MEDLINE]

Osteoclast size is controlled by Fra-2 through LIF/LIF-receptor signalling and hypoxia.

Bozec A, Bakiri L, Hoebertz A, Eferl R, Schilling AF, Komnenovic V, Scheuch H, Priemel M, Stewart CL, Amling M, Wagner EF.
Nature. 2008 Jul 10;454(7201):221-5. Epub 2008 Jun 11.

PMID : 18548006 [PubMed - indexed for MEDLINE]

Manufacture of degradable polymeric scaffolds for bone regeneration.

Ge Z, Jin Z, Cao T.
Biomed Mater. 2008 Jun;3(2):22001. Epub 2008 Jun 3. Review.

PMID : 18523339 [PubMed - indexed for MEDLINE]

Neurogenesis and asymmetric cell division.

Zhong W, Chia W.
Curr Opin Neurobiol. 2008 Feb;18(1):4-11. Epub 2008 May 29. Review.

PMID : 18513950 [PubMed - indexed for MEDLINE]

Degradation of electrospun nanofiber scaffold by short wave length ultraviolet radiation treatment and its potential applications in tissue engineering.

Yixiang D, Yong T, Liao S, Chan CK, Ramakrishna S.
Tissue Eng Part A. 2008 Aug;14(8):1321-9.

PMID : 18466068 [PubMed - indexed for MEDLINE]

In vivo study of anterior cruciate ligament regeneration using mesenchymal stem cells and silk scaffold.

Fan H, Liu H, Wong EJ, Toh SL, Goh JC.
Biomaterials. 2008 Aug;29(23):3324-37. Epub 2008 May 6.

PMID : 18462787 [PubMed - indexed for MEDLINE]

The time is right: proteome biology of stem cells.

Whetton AD, Williamson AJ, Krijgsveld J, Lee BH, Lemischka I, Oh S, Pera M, Mummery C, Heck AJ.
Cell Stem Cell. 2008 Mar 6;2(3):215-7. Review.

PMID : 18383624 [PubMed - indexed for MEDLINE]

Selection against undifferentiated human embryonic stem cells by a cytotoxic antibody recognizing podocalyxin-like protein-1.

Choo AB, Tan HL, Ang SN, Fong WJ, Chin A, Lo J, Zheng L, Hentze H, Philp RJ, Oh SK, Yap M.
Stem Cells. 2008 Jun;26(6):1454-63. Epub 2008 Mar 20.

PMID : 18356574 [PubMed - indexed for MEDLINE]

Osteogenic and adipogenic induction potential of human periodontal cells.

Zhou Y, Hutmacher DW, Sae-Lim V, Zhou Z, Woodruff M, Lim TM.
J Periodontol. 2008 Mar;79(3):525-34.

PMID : 18315436 [PubMed - indexed for MEDLINE]

The JAK/STAT pathway positively regulates DPP signaling in the Drosophila germline stem cell niche.

Wang L, Li Z, Cai Y.
J Cell Biol. 2008 Feb 25;180(4):721-8. Epub 2008 Feb 18.

PMID : 18283115 [PubMed - indexed for MEDLINE]

A TAG1-APP signalling pathway through Fe65 negatively modulates neurogenesis.

Ma QH, Futagawa T, Yang WL, Jiang XD, Zeng L, Takeda Y, Xu RX, Bagnard D, Schachner M, Furley AJ, Karagogeos D, Watanabe K, Dawe GS, Xiao ZC.
Nat Cell Biol. 2008 Mar;10(3):283-94. Epub 2008 Feb 17. Erratum in: Nat Cell Biol. 2008 Apr;10(4):497.

PMID : 18278038 [PubMed - indexed for MEDLINE]

Efficient expansion of clinical-grade human fibroblasts on microcarriers: cells suitable for ex vivo expansion of clinical-grade hESCs.

Phillips BW, Lim RY, Tan TT, Rust WL, Crook JM.
J Biotechnol. 2008 Mar 20;134(1-2):79-87. Epub 2008 Jan 8.

PMID : 18261818 [PubMed - indexed for MEDLINE]

Polyelectrolyte complex membranes for specific cell adhesion.

Wan AC, Tai BC, Schumacher KM, Schumacher A, Chin SY, Ying JY.
Langmuir. 2008 Mar 18;24(6):2611-7. Epub 2008 Feb 9.

PMID : 18260679 [PubMed - indexed for MEDLINE]

Tprg, a gene predominantly expressed in skin, is a direct target of the transcription factor p63.

Antonini D, Dentice M, Mahtani P, De Rosa L, Della Gatta G, Mandinova A, Salvatore D, Stupka E, Missero C.
J Invest Dermatol. 2008 Jul;128(7):1676-85. Epub 2008 Feb 7.

PMID : 18256694 [PubMed - indexed for MEDLINE]

Runx1 is involved in primitive erythropoiesis in the mouse.

Yokomizo T, Hasegawa K, Ishitobi H, Osato M, Ema M, Ito Y, Yamamoto M, Takahashi S.
Blood. 2008 Apr 15;111(8):4075-80. Epub 2008 Feb 4.

PMID : 18250229 [PubMed - indexed for MEDLINE]

Comparison of osteogenesis of human embryonic stem cells within 2D and 3D culture systems.

Tian XF, Heng BC, Ge Z, Lu K, Rufaihah AJ, Fan VT, Yeo JF, Cao T.
Scand J Clin Lab Invest. 2008;68(1):58-67.

PMID : 18224557 [PubMed - indexed for MEDLINE]

Basic fibroblast growth factor-induced neuronal differentiation of mouse bone marrow stromal cells requires FGFR-1, MAPK/ERK, and transcription factor AP-1.

Yang H, Xia Y, Lu SQ, Soong TW, Feng ZW.
J Biol Chem. 2008 Feb 29;283(9):5287-95. Epub 2008 Jan 2.

PMID : 18171671 [PubMed - indexed for MEDLINE]

Escape from suppression: tumor-specific effector cells outcompete regulatory T cells following stem-cell transplantation.

Mirmonsef P, Tan G, Zhou G, Morino T, Noonan K, Borrello I, Levitsky HI.
Blood. 2008 Feb 15;111(4):2112-21. Epub 2007 Dec 6.

PMID : 18063750 [PubMed - indexed for MEDLINE]

MicroRNA-134 modulates the differentiation of mouse embryonic stem cells, where it causes post-transcriptional attenuation of Nanog and LRH1.

Tay YM, Tam WL, Ang YS, Gaughwin PM, Yang H, Wang W, Liu R, George J, Ng HH, Perera RJ, Lufkin T, Rigoutsos I, Thomson AM, Lim B.
Stem Cells. 2008 Jan;26(1):17-29. Epub 2007 Oct 4.

PMID : 17916804 [PubMed - indexed for MEDLINE]

Three-dimensional fibrous PLGA/HAp composite scaffold for BMP-2 delivery.

Nie H, Soh BW, Fu YC, Wang CH.
Biotechnol Bioeng. 2008 Jan 1;99(1):223-34.

PMID : 17570710 [PubMed - indexed for MEDLINE]

Interaction of cells and nanofiber scaffolds in tissue engineering.

Venugopal J, Low S, Choon AT, Ramakrishna S.
J Biomed Mater Res B Appl Biomater. 2008 Jan;84(1):34-48. Review.

PMID : 17477388 [PubMed - indexed for MEDLINE]

Mucocutaneous junction of eyelid and lip: a study of the transition zone using epithelial cell markers.

Riau AK, Barathi VA, Beuerman RW.
Curr Eye Res. 2008 Nov;33(11):912-22.

PMID : 19085373 [PubMed - indexed for MEDLINE]

A DNA transposon-based approach to validate oncogenic mutations in the mouse.

Su Q, Prosser HM, Campos LS, Ortiz M, Nakamura T, Warren M, Dupuy AJ, Jenkins NA, Copeland NG, Bradley A, Liu P.
Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):19904-9. Epub 2008 Dec 8.

PMID : 19064922 [PubMed - indexed for MEDLINE]

Purification, crystallization and preliminary X-ray diffraction analysis of the HMG domain of Sox17 in complex with DNA.

Ng CK, Palasingam P, Venkatachalam R, Baburajendran N, Cheng J, Jauch R, Kolatkar PR.
Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 Dec 1;64(Pt 12):1184-7. Epub 2008 Nov 28.

PMID : 19052383 [PubMed - indexed for MEDLINE]

Iron and the translation of the amyloid precursor protein (APP) and ferritin mRNAs: riboregulation against neural oxidative damage in Alzheimer's disease.

Rogers JT, Bush AI, Cho HH, Smith DH, Thomson AM, Friedlich AL, Lahiri DK, Leedman PJ, Huang X, Cahill CM.
Biochem Soc Trans. 2008 Dec;36(Pt 6):1282-7. Review.

PMID : 19021541 [PubMed - indexed for MEDLINE]

Technique to accurately quantify collagen content in hyperconfluent cell culture.

See EY, Toh SL, Goh JC.
J Mol Histol. 2008 Dec;39(6):643-7. Epub 2008 Nov 8.

PMID : 18998216 [PubMed - indexed for MEDLINE]

A thixotropic nanocomposite gel for three-dimensional cell culture.

Pek YS, Wan AC, Shekaran A, Zhuo L, Ying JY.
Nat Nanotechnol. 2008 Nov;3(11):671-5. Epub 2008 Sep 28.

PMID : 18989333 [PubMed - indexed for MEDLINE]

REST regulates distinct transcriptional networks in embryonic and neural stem cells.

Johnson R, Teh CH, Kunarso G, Wong KY, Srinivasan G, Cooper ML, Volta M, Chan SS, Lipovich L, Pollard SM, Karuturi RK, Wei CL, Buckley NJ, Stanton LW.
PLoS Biol. 2008 Oct 28;6(10):e256.

PMID : 18959480 [PubMed - indexed for MEDLINE]

The biological and ethical basis of the use of human embryonic stem cells for in vitro test systems or cell therapy.

Leist M, Bremer S, Brundin P, Hescheler J, Kirkeby A, Krause KH, Poerzgen P, Puceat M, Schmidt M, Schrattenholz A, Zak NB, Hentze H.
ALTEX. 2008;25(3):163-90.

PMID : 18841314 [PubMed - indexed for MEDLINE]

Role of Cdx2 and cell polarity in cell allocation and specification of trophectoderm and inner cell mass in the mouse embryo.

Jedrusik A, Parfitt DE, Guo G, Skamagki M, Grabarek JB, Johnson MH, Robson P, Zernicka-Goetz M.
Genes Dev. 2008 Oct 1;22(19):2692-706.

PMID : 18832072 [PubMed - indexed for MEDLINE]

Stem cell transplantation programme at Singapore General Hospital.

Koh M, Goh Y, Tan P, Koh L, Hwang W, Loh Y, Tan D, Ng H, Chuah C, Lim T, Niam M, Suck G, Chan M, Phang C, Lee J, Wee V, Ng H, Lim Ch, Yiu R, Kam G, Ang A, Linn Y.
Bone Marrow Transplant. 2008 Aug;42 Suppl 1:S121-S124. Review.

PMID : 18724284 [PubMed - indexed for MEDLINE]

Sall4 regulates distinct transcription circuitries in different blastocyst-derived stem cell lineages.

Lim CY, Tam WL, Zhang J, Ang HS, Jia H, Lipovich L, Ng HH, Wei CL, Sung WK, Robson P, Yang H, Lim B.
Cell Stem Cell. 2008 Nov 6;3(5):543-54. Epub 2008 Sep 18.

PMID : 18804426 [PubMed - indexed for MEDLINE]

Transcriptional and epigenetic regulations of embryonic stem cells.

Ng JH, Heng JC, Loh YH, Ng HH.
Mutat Res. 2008 Dec 1;647(1-2):52-8. Epub 2008 Aug 20. Review.

PMID : 18778721 [PubMed - indexed for MEDLINE]

RUNX3 attenuates beta-catenin/T cell factors in intestinal tumorigenesis.

Ito K, Lim AC, Salto-Tellez M, Motoda L, Osato M, Chuang LS, Lee CW, Voon DC, Koo JK, Wang H, Fukamachi H, Ito Y.
Cancer Cell. 2008 Sep 9;14(3):226-37. Erratum in: Cancer Cell. 2009 Mar 3;15(3):240.

PMID : 18772112 [PubMed - indexed for MEDLINE]

Attachment and growth of human embryonic stem cells on microcarriers.

Phillips BW, Horne R, Lay TS, Rust WL, Teck TT, Crook JM.
J Biotechnol. 2008 Nov 6;138(1-2):24-32. Epub 2008 Aug 14.

PMID : 18771697 [PubMed - indexed for MEDLINE]

Functional genomics of cancer.

Liu ET.
Curr Opin Genet Dev. 2008 Jun;18(3):251-6. Epub 2008 Aug 28. Review.

PMID : 18691651 [PubMed - indexed for MEDLINE]

TGFbeta and SMADs talk to NANOG in human embryonic stem cells.

Jiang J, Ng HH.
Cell Stem Cell. 2008 Aug 7;3(2):127-8.

PMID : 18682233 [PubMed - in process]

Biocompatibility of silica coated NaYF(4) upconversion fluorescent nanocrystals.

Abdul Jalil R, Zhang Y.
Biomaterials. 2008 Oct;29(30):4122-8.

PMID : 18675453 [PubMed - indexed for MEDLINE]

Hydroxysafflor yellow A enhances survival of vascular endothelial cells under hypoxia via upregulation of the HIF-1 alpha-VEGF pathway and regulation of Bcl-2/Bax.

Ji DB, Zhu MC, Zhu B, Zhu YZ, Li CL, Ye J, Zhu HB.
J Cardiovasc Pharmacol. 2008 Aug;52(2):191-202.

PMID : 18670359 [PubMed - indexed for MEDLINE]

Manipulation of immune system via immortal bone marrow stem cells.

Ruedl C, Khameneh HJ, Karjalainen K.
Int Immunol. 2008 Sep;20(9):1211-8. Epub 2008 Jul 21.

PMID : 18644831 [PubMed - indexed for MEDLINE]

FKBP family proteins: immunophilins with versatile biological functions.

Kang CB, Hong Y, Dhe-Paganon S, Yoon HS.
Neurosignals. 2008;16(4):318-25. Epub 2008 Jul 18. Review.

PMID : 18635947 [PubMed - indexed for MEDLINE]

c-Abl is involved in high glucose-induced apoptosis in embryonic E12.5 cortical neural progenitor cells from the mouse brain.

Jia DY, Du ZH, Liu SM, Liu HJ, Wang FW, Ling EA, Liu K, Hao AJ.
J Neurochem. 2008 Aug;106(4):1720-30. Epub 2008 Jul 4.

PMID : 18624912 [PubMed - indexed for MEDLINE]

Cardiomyocyte production in mass suspension culture: embryonic stem cells as a source for great amounts of functional cardiomyocytes.

Niebruegge S, Nehring A, Bär H, Schroeder M, Zweigerdt R, Lehmann J.
Tissue Eng Part A. 2008 Oct;14(10):1591-601.

PMID : 18593268 [PubMed - indexed for MEDLINE]

Transmembrane protein 18 enhances the tropism of neural stem cells for glioma cells.

Jurvansuu J, Zhao Y, Leung DS, Boulaire J, Yu YH, Ahmed S, Wang S.
Cancer Res. 2008 Jun 15;68(12):4614-22.

PMID : 18559506 [PubMed - indexed for MEDLINE]

Folic acid supplementation affects apoptosis and differentiation of embryonic neural stem cells exposed to high glucose.

Jia DY, Liu HJ, Wang FW, Liu SM, Ling EA, Liu K, Hao AJ.
Neurosci Lett. 2008 Jul 25;440(1):27-31. Epub 2008 May 18.

PMID : 18541378 [PubMed - indexed for MEDLINE]

DACT3 is an epigenetic regulator of Wnt/beta-catenin signaling in colorectal cancer and is a therapeutic target of histone modifications.

Jiang X, Tan J, Li J, Kivimäe S, Yang X, Zhuang L, Lee PL, Chan MT, Stanton LW, Liu ET, Cheyette BN, Yu Q.
Cancer Cell. 2008 Jun;13(6):529-41.

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HSV-1 amplicon viral vector-mediated gene transfer to human bone marrow-derived mesenchymal stem cells.

Ho IA, Chan KY, Miao L, Shim WS, Guo CM, Cheang P, Hui KM, Lam PY.
Cancer Gene Ther. 2008 Sep;15(9):553-62. Epub 2008 Jun 6.

PMID : 18535622 [PubMed - indexed for MEDLINE]

Leukemia inhibitory factor regulates microvessel density by modulating oxygen-dependent VEGF expression in mice.

Kubota Y, Hirashima M, Kishi K, Stewart CL, Suda T.
J Clin Invest. 2008 Jul;118(7):2393-403.

PMID : 18521186 [PubMed - indexed for MEDLINE]

Study of gene expression profile during cord blood-associated megakaryopoiesis.

Lim CK, Hwang WY, Aw SE, Sun L.
Eur J Haematol. 2008 Sep;81(3):196-208. Epub 2008 May 27.

PMID : 18510698 [PubMed - indexed for MEDLINE]

Therapeutic siRNAs for dominant genetic skin disorders including pachyonychia congenita.

Leachman SA, Hickerson RP, Hull PR, Smith FJ, Milstone LM, Lane EB, Bale SJ, Roop DR, McLean WH, Kaspar RL.
J Dermatol Sci. 2008 Sep;51(3):151-7. Epub 2008 May 20. Review.

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Beta1 integrin deletion from the basal compartment of the mammary epithelium affects stem cells.

Taddei I, Deugnier MA, Faraldo MM, Petit V, Bouvard D, Medina D, Fässler R, Thiery JP, Glukhova MA.
Nat Cell Biol. 2008 Jun;10(6):716-22. Epub 2008 May 11.

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T-cell factor 3 regulates embryonic stem cell pluripotency and self-renewal by the transcriptional control of multiple lineage pathways.

Tam WL, Lim CY, Han J, Zhang J, Ang YS, Ng HH, Yang H, Lim B.
Stem Cells. 2008 Aug;26(8):2019-31. Epub 2008 May 8.

PMID : 18467660 [PubMed - indexed for MEDLINE]

A gel-free 3D microfluidic cell culture system.

Ong SM, Zhang C, Toh YC, Kim SH, Foo HL, Tan CH, van Noort D, Park S, Yu H.
Biomaterials. 2008 Aug;29(22):3237-44. Epub 2008 May 2.

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Autocrine fibroblast growth factor 2 increases the multipotentiality of human adipose-derived mesenchymal stem cells.

Rider DA, Dombrowski C, Sawyer AA, Ng GH, Leong D, Hutmacher DW, Nurcombe V, Cool SM.
Stem Cells. 2008 Jun;26(6):1598-608. Epub 2008 Mar 20.

PMID : 18356575 [PubMed - indexed for MEDLINE]

PDGF, TGF-beta, and FGF signaling is important for differentiation and growth of mesenchymal stem cells (MSCs): transcriptional profiling can identify markers and signaling pathways important in differentiation of MSCs into adipogenic, chondrogenic, and osteogenic lineages.

Ng F, Boucher S, Koh S, Sastry KS, Chase L, Lakshmipathy U, Choong C, Yang Z, Vemuri MC, Rao MS, Tanavde V.
Blood. 2008 Jul 15;112(2):295-307. Epub 2008 Mar 10.

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Cell therapy for diabetes mellitus: an opportunity for stem cells?

Soria B, Bedoya FJ, Tejedo JR, Hmadcha A, Ruiz-Salmerón R, Lim S, Martin F.
Cells Tissues Organs. 2008;188(1-2):70-7. Epub 2008 Feb 29.

PMID : 18305378 [PubMed - indexed for MEDLINE]

Common features of umbilical cord epithelial cells and epidermal keratinocytes.

Ruetze M, Gallinat S, Lim IJ, Chow E, Phan TT, Staeb F, Wenck H, Deppert W, Knott A.
J Dermatol Sci. 2008 Jun;50(3):227-31. Epub 2008 Feb 1. No abstract available.

PMID : 18242061 [PubMed - indexed for MEDLINE]

Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer.

Varambally S, Cao Q, Mani RS, Shankar S, Wang X, Ateeq B, Laxman B, Cao X, Jing X, Ramnarayanan K, Brenner JC, Yu J, Kim JH, Han B, Tan P, Kumar-Sinha C, Lonigro RJ, Palanisamy N, Maher CA, Chinnaiyan AM.
Science. 2008 Dec 12;322(5908):1695-9. Epub 2008 Nov 13.

PMID : 19008416 [PubMed - indexed for MEDLINE]

MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation.

Tay Y, Zhang J, Thomson AM, Lim B, Rigoutsos I.
Nature. 2008 Oct 23;455(7216):1124-8. Epub 2008 Sep 17.

PMID : 18806776 [PubMed - indexed for MEDLINE]

Nanotechnology for nanomedicine and delivery of drugs.

Venugopal J, Prabhakaran MP, Low S, Choon AT, Zhang YZ, Deepika G, Ramakrishna S.
Curr Pharm Des. 2008;14(22):2184-200. Review.

PMID : 18781971 [PubMed - indexed for MEDLINE]

The transcription factor Zfp281 controls embryonic stem cell pluripotency by direct activation and repression of target genes.

Wang ZX, Teh CH, Chan CM, Chu C, Rossbach M, Kunarso G, Allapitchay TB, Wong KY, Stanton LW.
Stem Cells. 2008 Nov;26(11):2791-9. Epub 2008 Aug 28.

PMID : 18757296 [PubMed - in process]

An HMM approach to genome-wide identification of differential histone modification sites from ChIP-seq data.

Xu H, Wei CL, Lin F, Sung WK.
Bioinformatics. 2008 Oct 15;24(20):2344-9. Epub 2008 Jul 29.

PMID : 18667444 [PubMed - indexed for MEDLINE]

Viscoelastic behaviour of human mesenchymal stem cells.

Tan SC, Pan WX, Ma G, Cai N, Leong KW, Liao K.
BMC Cell Biol. 2008 Jul 22; 9:40 .

PMID : 18644160 [PubMed - indexed for MEDLINE]

Genetic evidence of PEBP2beta-independent activation of Runx1 in the murine embryo.

Yokomizo T, Yanagida M, Huang G, Osato M, Honda C, Ema M, Takahashi S, Yamamoto M, Ito Y.
Int J Hematol. 2008 Sep;88(2):134-8. Epub 2008 Jul 2.

PMID : 18594778 [PubMed - indexed for MEDLINE]

Highly enriched cardiomyocytes from human embryonic stem cells.

Xu XQ, Zweigerdt R, Soo SY, Ngoh ZX, Tham SC, Wang ST, Graichen R, Davidson B, Colman A, Sun W.
Cytotherapy. 2008;10(4):376-89.

PMID : 18574770 [PubMed - indexed for MEDLINE]

Chemically defined medium supporting cardiomyocyte differentiation of human embryonic stem cells.

Xu XQ, Graichen R, Soo SY, Balakrishnan T, Rahmat SN, Sieh S, Tham SC, Freund C, Moore J, Mummery C, Colman A, Zweigerdt R, Davidson BP.
Differentiation. 2008 Nov;76(9):958-70. Epub 2008 Jun 13.

PMID : 18557764 [PubMed - indexed for MEDLINE]

Human embryonic stem cells may display higher resistance to genotoxic stress as compared to primary explanted somatic cells.

Vinoth KJ, Heng BC, Poonepalli A, Banerjee B, Balakrishnan L, Lu K, Hande MP, Cao T.
Stem Cells Dev. 2008 Jun;17(3):599-607.

PMID : 18498216 [PubMed - indexed for MEDLINE]

Cross-species de novo identification of cis-regulatory modules with GibbsModule: application to gene regulation in embryonic stem cells.

Xie D, Cai J, Chia NY, Ng HH, Zhong S.
Genome Res. 2008 Aug;18(8):1325-35. Epub 2008 May 15.

PMID : 18490265 [PubMed - indexed for MEDLINE]

Bone-marrow-derived cells that home to acoustic deafened cochlea preserved their hematopoietic identity.

Tan BT, Lee MM, Ruan R.
J Comp Neurol. 2008 Jul 10;509(2):167-79.

PMID : 18461607 [PubMed - indexed for MEDLINE]

Development of dual-compartment perfusion bioreactor for serial coculture of hepatocytes and stellate cells in poly(lactic-co-glycolic acid)-collagen scaffolds.

Wen F, Chang S, Toh YC, Arooz T, Zhuo L, Teoh SH, Yu H.
J Biomed Mater Res B Appl Biomater. 2008 Oct;87(1):154-62.

PMID : 18431752 [PubMed - indexed for MEDLINE]